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Image Search Results
Journal: Journal of Nanobiotechnology
Article Title: Manganese-loaded carbon nanoparticles ameliorate ANCA-associated vasculitis by inhibiting ferroptosis
doi: 10.1186/s12951-025-03725-z
Figure Lengend Snippet: Ferroptosis is present during ANCA-GN progression. ( A ) Expression of serum ferritin in healthy individuals ( n = 12) and ANCA-GN patients ( n = 28); ( B ) Expression of serum MDA in healthy individuals ( n = 12) and ANCA-GN patients ( n = 28); ( C ) Serum MnSOD activity in healthy individuals ( n = 12) and ANCA-GN patients ( n = 28); ( D ) Correlation analysis between serum cf-DNA and MDA in ANCA-GN patients ( n = 28); ( E ) Correlation analysis between serum MnSOD activity and MDA in ANCA-GN patients ( n = 28); ( F ) Expression of TFR1 in renal tissues of ANCA-GN patients and MPO-AAV rats, with glomeruli indicated by dashed lines, scale bar = 20 μm; ( G ) Western Blot analysis of changes in ferroptosis-related protein expression in MPO-AAV rats ( n = 3). * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001 AAV: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis; ANCA-GN: ANCA-associated glomerulonephritis; MPO: Myeloperoxidase; HC: Health control; EAV: Experimental autoimmune vasculitis; HAS: Human serum albumin
Article Snippet: Western blotting (WB) was performed using specific
Techniques: Expressing, Activity Assay, Western Blot, Control